Description

Phenolphthalein White CAS: 77-09-8 | MF: C20H14O4 | MW: 318.32, Buy now for reliable and Reproducible results from Tristains indicators.

Phenolphthalein Indicator White (CAS No. 77-09-8) is a white crystalline organic compound, which is a member of the phthalein family. It is well known to be used as an acid-base pH indicator. In acidic conditions, phenolphthalein is colorless and changes to pink and then deep red in alkaline and cyanide carbonate solutions, respectively. It is colorless at a pH less than 8.5 and turns pink to deep red at a pH greater than 9.0. The molecular formula of this compound is C20H14O4, and it does not dissolve easily in water but does dissolve easily in organic solvents. Because of these characteristics, Phenolphthalein Indicator White is widely utilized in analytical chemistry, educational and industrial laboratories.

Applications

Acid–Base Titrations: Typically, it is employed in determining titration endpoints in analytical chemistry processes with a high level of accuracy.
Educational Demonstrations: It suits academic laboratory teaching well because it possesses a distinctly observable color change with the experimental changes in pH and titration.
Institutes of Quality Control: Used in industrial and pharmaceutical quality control testing where sensitivity and reliability is needed.
Research Chemistry: Applied to analytical investigations on alkaline reactions and compound reaction analysis.

Key features

Highly Visible Transitions: Gives definite and distinct color transitions with a change in pH.
User-Friendly pH Detection: Properly detects changes in pH between 8.5 and 10.
Versatile Usage: Applicable to non-aqueous and aqueous chemical systems.
Stable and Low Maintenance: Stable at normal laboratory temperatures.
Cost-Effective Performance: Provides professional-grade accuracy at a cost effective laboratory use.

General Description

Phenolphthalein Indicator White (CAS No. 77-09-8) is an organic indicator (commonly used) in reliable acid-base pH testing. Being a crystalline white powder made of the phthalein group of dyes, it has been known to perform reliably in laboratory tests used in the analysis and education of chemistry students. This indicator has a molecular weight of 318.32 g/mol and thus is given a dependable sensitivity in a variety of chemical uses. Phenolphthalein Indicator White is highly soluble in alcohol and other organic solvents at a neutral pH and therefore is compatible with a wide variety of reaction conditions where solvent permeability is necessary.

Want to buy Phenolphthalein Indicator White? This product is supplied under the reputed TriStains indicators range, which has been trusted by chemists, educators, researchers, and students to yield repeatable and reliable results. Phenolphthalein Indicator White is still a favorite in acid-base titrations and in other applications of analytical chemistry when precision, simplicity and reliability are of importance. Buy Phenolphthalein Indicator White from the TriStains because it provides reliable, precise, and repeatable results.

About Brand

TriStains provides a marketplace for histology and biological stains, which is comprehensive enough to encompass the peculiar requirements of laboratories specializing in Histology, Cytology, Microbiology, and Hematology. With a reputation for exceeding quality expectations, TriStains performance is outstanding which allows for resolution of cell and tissue components fundamental to life sciences to be clearly visualized. Each product under TriStains series is validated for accuracy, reliability and consistency. TriStains, which manufactures and markets stains and indicators in various packing, offers laboratories turn key solutions for all their staining and indicator needs, improving accuracy in every experiment.

Additional information

CAS No	77-09-8
Synonyms	3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone
MW	318.32
MF	C20H14O4
Brand	Tristains
Size	100g, 10g, 25g, 50g

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TECHNICAL INFORMATION

Alternate Names	3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone
Application	Phenolphthalein is a commonly used colorimetric pH indicator
CAS Number	77-09-8
Molecular Weight	318.32
Molecular Formula	C₂₀H₁₄O₄

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Phenolphthalein is a chemical that is commonly used as a colorimetric pH indicator. The compound has been observed to turn orange at pH <0, clear between pH 0-8.2, fuchsia between pH 8.2-12, and clear again at a pH above 12. It has been postulated that the mutagenic effects of Phenolphthalein at high doses can be attributed the enhancement intracellular free oxygen radicals. The compound has also been observed to induce mitotic abnormalities and micronuclei with kinetochores in vitro. In Syrian hamster embryos treated with 10-40 μM of Phenolpthalein a significant number of chromosomal aberrations occurred at the hprt locus. On human breast cancer cells Phenolphthalein has been observed to have weak estrogenic effects.

TECHNICAL INFORMATION

Appearance	Powder
Physical State	Solid
Solubility	Soluble in water (partly), chloroform (slightly), acetone, ethanol (50 mg/ml), and methanol (10 mg/ml).
Storage	Store at room temperature
Melting Point	261-263° C (lit.)
Boiling Point	~557.8° C at 760 mmHg (Predicted)
Density	1.30 g/cm³ at 20
Refractive Index	n²⁰_D 1.69 (Predicted)
IC50	GPR55: IC₅₀ = 6.67 µM (human)
Ki Data	TS: K_i= 1.2 µM (human); Thymidylate synthase: K_i= 1.4 µM (Enterococcus faecalis); Thymidylate synthase: K_i= 4.7 µM (Escherichia coli K-12); Thymidylate synthase: K_i= 4.7 µM (Lactobacillus casei)
pK Values	pK_a: 9.7

SAFETY INFORMATION

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

WGK Germany	3
RTECS	SM8380000
PubChem CID	4764
Merck Index	14:7243
MDL Number	MFCD00005913
EC Number	201-004-7
Beilstein Registry	284423
SMILES	C1=CC=C2C(=C1)C(=O)OC2(C3=CC =C(C=C3)O)C4=CC=C(C=C4)O

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I10557

Phenolphthalein White

CAS No

77-09-8

Synonym(s)

3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone

Molecular Formula:

C₂₀H₁₄O₄

Molecular Weight:

318.32

EC Number:

201-004-7

Colour Index Number:

764

PubChem CID:

4764

MDL number:

MFCD00005913

Specification SDS Available pack size: 10g, 25g, 50g, 100g

CAS No	77-09-8
Synonyms	3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone
MW	318.32
MF	C20H14O4
Brand	Tristains
Size	100g, 10g, 25g, 50g

Alternate Names	3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone
Application	Phenolphthalein is a commonly used colorimetric pH indicator
CAS Number	77-09-8
Molecular Weight	318.32
Molecular Formula	C₂₀H₁₄O₄

Appearance	Powder
Physical State	Solid
Solubility	Soluble in water (partly), chloroform (slightly), acetone, ethanol (50 mg/ml), and methanol (10 mg/ml).
Storage	Store at room temperature
Melting Point	261-263° C (lit.)
Boiling Point	~557.8° C at 760 mmHg (Predicted)
Density	1.30 g/cm³ at 20
Refractive Index	n²⁰_D 1.69 (Predicted)
IC50	GPR55: IC₅₀ = 6.67 µM (human)
Ki Data	TS: K_i= 1.2 µM (human); Thymidylate synthase: K_i= 1.4 µM (Enterococcus faecalis); Thymidylate synthase: K_i= 4.7 µM (Escherichia coli K-12); Thymidylate synthase: K_i= 4.7 µM (Lactobacillus casei)
pK Values	pK_a: 9.7

WGK Germany	3
RTECS	SM8380000
PubChem CID	4764
Merck Index	14:7243
MDL Number	MFCD00005913
EC Number	201-004-7
Beilstein Registry	284423
SMILES	C1=CC=C2C(=C1)C(=O)OC2(C3=CC =C(C=C3)O)C4=CC=C(C=C4)O