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Tristains

S10061

Curcumin, C.I. 75300

$56.52 – $168.52

CAS No
458-37-7
Synonym(s)
Curcumin, C.I. 75300
Molecular Formula:
C21H20O6
Molecular Weight:
368.38
EC Number:
207-280-5
Colour Index Number:
75300
PubChem CID:
969516
MDL number:
MFCD00008365
Specification SDS

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Description

Buy High Quality Curcumin, C.I. 75300 (458-37-7) MF: C21H20O6 | MW: 368.38. from Tristains.

Curcumin (CI 75300) is a natural dye derived from the turmeric plant (Curcuma longa). Curcumin is a bright yellow-orange pigment that is soluble in ethanol and dimethyl sulfoxide (DMSO) but has limited solubility in water. The chemical formula of Curcumin is C21H20O6. It is also known as (E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane, Diferulylmethane, Natural Yellow 3. curcumin (CI 75300) stain offers a range of benefits in biological staining and analytical chemistry, making it a valuable tool in scientific research and industry.

“TriStains”, Histological Stains/Biological Stains that offer range of stains used in Histology, Cytology, Microbiology and Hematology laboratories. TriStains meet the highest quality standards and give excellent color performance of desired components of cells and tissue in life science laboratories. TriStains series products are carefully tested to ensure accurate, reliable, and reproducible results. Our products are available in different packaging sizes to allow you to get all types of stains & Indicators for your specific purposes from a single source.

In-addition Tristains also deals in numerous Laboratory Supplies, Chemicals, Equipment, Instruments, Reagents, Standard Solutions, Buffers, Histological Stains/Biological Stains & Indicators and many more, for more information please visit our website www.tristains.com or email to [email protected] we will be happy to help you. All Tristains Products are exclusively distributed by Dawn Scientific Inc (https://dawnscientific.com)

Application :

  • Curcumin is commonly used in biological staining techniques, particularly in histology and cytology.
  • Curcumin is used as a complexometric indicator for boron. It reacts with boric acid to form a red-colored compound, rosocyanine.

Benefits :

  • Gives reliable and accurate results
  • As an anti-inflammatory agent
  • Cost-effective and easy to use
Additional information
Weight N/A
Dimensions N/A
Brand

Size

25g, 5g
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TECHNICAL INFORMATION
Application  Curcumin is a yellow-orange dye, NOS2 regulator, and inhibitor of NF-κB, 5-LO, Cox-2, COP9, and p300/CBP.
CAS Number 458-37-7
Purity ≥95%
Molecular Weight 368.38
Molecular Formula  C21H20O6

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Refer to Certificate of Analysis for lot specific data (including water content).

Curcumin is a yellow-orange dye obtained from tumeric, the powdered root of Curcuma longa. Curcumin is employed in the preparation of curcuma paper, the detection of boron, and possesses a vast number of biological targets. Curcumin has been shown to inhibit NF-κB, possibly through inhibition of JNK (IC50=10 μM). Curcumin blocks amyloid peptide induced expression of: TNF-α, IL-1β, MCP-1, IL-8, and CCR5, regulates NOS2, inhibits IgE and Ag-induced degranulation of mast cells, inhibits 5-LO (5-lipoxygenase) (IC50=8 μM), Cox-2 (cyclooxygenase-2) (IC50=52 μM), the COP9 signalosome kinase (IC50=10 µM), and p300/CBP. This wide range of activities makes Curcumin an extremely useful tool for developing novel analogues and uses.

TECHNICAL INFORMATION

Appearance : Powder
Physical State : Solid
Solubility : Soluble in water (1 mg/ml), and ethanol (1%). Insoluble in acetone.
Derived From : Turmeric rhizome
Solubility : Soluble in DMSO (25 mg/ml), acetic acid, 0.1M NaOH, 10mM Na2CO3, acetone, water (< 0.1 mg/ml), and chloroform. Insoluble in ethanol.
Storage : Store at room temperature
Melting Point : 170-175° C
Boiling Point : ~591.4° C at 760 mmHg (Predicted)
Density : ~1.3 g/cm3 (Predicted)
Refractive Index : n20D 1.42
IC50 : 5-lipoxygenase: IC50 = 8 µM; cyclooxygenase: IC50 = 52 µM; nitric oxide synthase in activated macrophages: IC50 = 6 µM

SAFETY INFORMATION

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany : 3
PubChem CID :
969516
RTECS  :
MI5230000
Merck Index :
14: 2673
MDL Number :
MFCD00008365
EC Number :
207-280-5
Beilstein Registry :
2306965
SMILES :
COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C=C2)O)OC)O

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