Description

Phenolphthalein White CAS: 77-09-8 | MF: C20H14O4 | MW: 318.32, Buy now for accurate and Reproducible results from Tristains indicators. All Tristains products are exclusively distributed by Dawn Scientific Inc.

Phenolphthalein Indicator (WHITE) is a white colored powdered organic compound which belongs to the class of phthalein family. It is widely used as an acid-base indicating agent. Phenolphthalein is colorless in acidic solutions and turns pink to deep red in alkaline solutions. This chemical remains colourless below the pH value of 8.5 and attains a pink to deep red hue colour when the value of the pH is above 9.0. Phenolphthalein Indicator (WHITE)has a chemical formula of C20H14O4. It is sparingly soluble in water but soluble in alcohol and other organic solvents. Phenolphthalein is a chemical compound commonly used as a pH indicator and in various other applications.

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Application :

Phenolphthalein indicator white is primarily used as a pH indicator. It changes color depending on the acidity or alkalinity of a solution. It is commonly used in acid-base titrations.
It is frequently used in educational settings to demonstrate pH concepts and titration techniques due to its clear and easily observable color change.

Benefits :

Provides a clear and distinct color change
Sensitive and versatile
Long shelf life and affordable

Additional information

CAS NO	77-09-8
Synonyms	3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone
MW	318.32
MF	C20H14O4
Brand	Tristains
Size	100g, 10g, 25g, 50g

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TECHNICAL INFORMATION

Alternate Names	3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone
Application	Phenolphthalein is a commonly used colorimetric pH indicator
CAS Number	77-09-8
Molecular Weight	318.32
Molecular Formula	C₂₀H₁₄O₄

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Phenolphthalein is a chemical that is commonly used as a colorimetric pH indicator. The compound has been observed to turn orange at pH <0, clear between pH 0-8.2, fuchsia between pH 8.2-12, and clear again at a pH above 12. It has been postulated that the mutagenic effects of Phenolphthalein at high doses can be attributed the enhancement intracellular free oxygen radicals. The compound has also been observed to induce mitotic abnormalities and micronuclei with kinetochores in vitro. In Syrian hamster embryos treated with 10-40 μM of Phenolpthalein a significant number of chromosomal aberrations occurred at the hprt locus. On human breast cancer cells Phenolphthalein has been observed to have weak estrogenic effects.

TECHNICAL INFORMATION

Appearance	Powder
Physical State	Solid
Solubility	Soluble in water (partly), chloroform (slightly), acetone, ethanol (50 mg/ml), and methanol (10 mg/ml).
Storage	Store at room temperature
Melting Point	261-263° C (lit.)
Boiling Point	~557.8° C at 760 mmHg (Predicted)
Density	1.30 g/cm³ at 20
Refractive Index	n²⁰_D 1.69 (Predicted)
IC50	GPR55: IC₅₀ = 6.67 µM (human)
Ki Data	TS: K_i= 1.2 µM (human); Thymidylate synthase: K_i= 1.4 µM (Enterococcus faecalis); Thymidylate synthase: K_i= 4.7 µM (Escherichia coli K-12); Thymidylate synthase: K_i= 4.7 µM (Lactobacillus casei)
pK Values	pK_a: 9.7

SAFETY INFORMATION

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

WGK Germany	3
RTECS	SM8380000
PubChem CID	4764
Merck Index	14:7243
MDL Number	MFCD00005913
EC Number	201-004-7
Beilstein Registry	284423
SMILES	C1=CC=C2C(=C1)C(=O)OC2(C3=CC =C(C=C3)O)C4=CC=C(C=C4)O

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I10557

Phenolphthalein White

CAS No

77-09-8

Synonym(s)

3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone

Molecular Formula:

C₂₀H₁₄O₄

Molecular Weight:

318.32

EC Number:

201-004-7

Colour Index Number:

764

PubChem CID:

4764

MDL number:

MFCD00005913

Specification SDS

CAS NO	77-09-8
Synonyms	3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone
MW	318.32
MF	C20H14O4
Brand	Tristains
Size	100g, 10g, 25g, 50g

Alternate Names	3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone
Application	Phenolphthalein is a commonly used colorimetric pH indicator
CAS Number	77-09-8
Molecular Weight	318.32
Molecular Formula	C₂₀H₁₄O₄

Appearance	Powder
Physical State	Solid
Solubility	Soluble in water (partly), chloroform (slightly), acetone, ethanol (50 mg/ml), and methanol (10 mg/ml).
Storage	Store at room temperature
Melting Point	261-263° C (lit.)
Boiling Point	~557.8° C at 760 mmHg (Predicted)
Density	1.30 g/cm³ at 20
Refractive Index	n²⁰_D 1.69 (Predicted)
IC50	GPR55: IC₅₀ = 6.67 µM (human)
Ki Data	TS: K_i= 1.2 µM (human); Thymidylate synthase: K_i= 1.4 µM (Enterococcus faecalis); Thymidylate synthase: K_i= 4.7 µM (Escherichia coli K-12); Thymidylate synthase: K_i= 4.7 µM (Lactobacillus casei)
pK Values	pK_a: 9.7

WGK Germany	3
RTECS	SM8380000
PubChem CID	4764
Merck Index	14:7243
MDL Number	MFCD00005913
EC Number	201-004-7
Beilstein Registry	284423
SMILES	C1=CC=C2C(=C1)C(=O)OC2(C3=CC =C(C=C3)O)C4=CC=C(C=C4)O