Description

Quercetin dihydrate CAS: 6151-25-3 | MF: C15H10O7•2H2O | MW: 338.27, Buy Histological Stains & Dyes for Histology, Cytology, Microbiology, Hematology & Biology Lab from TriStains.

Quercetin Dihydrate (CAS: 6151-25-3) is a yellow crystalline powder also known by its chemical names 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one dihydrate and 3,3′,4′,5,7-Pentahydroxyflavone dihydrate. It weighs 338.27 and has a molecular formula of C15H10O7•2H2O. It is a research-grade compound available under the TriStains range and is common in the laboratory and science-related uses. Quercetin Dihydrate is a flavonoid, which is a naturally occurring antioxidant and biologically important compound.

Applications

Quercetin Dihydrate is widely used in cell biology research and experimental studies on oxidative stress and cellular response mechanisms.

Key features

Antioxidant properties: Quercetin Dihydrate is very effective in neutralizing and decreasing the oxidative damage of the biological systems by neutralizing the free radicals.
Reliable results: The compound provides stable and reliable results in both laboratory work and research.
Cost-effective: At competitive and affordable prices, it is appropriate to be used in regular laboratories.

General Description

Quercetin Dihydrate (CAS: 6151-25-3) is a high purity laboratory reagent offered by TriStains. Having a molecular formula of C15H10O72H2O and a molecular weight of 338.27, it can be used across a broad spectrum of cell biology and biochemical research work.

Want to buy Quercetin Dihydrate? To be informed about buying opportunities, supply, and cost of Quercetin Dihydrate, customers can visit the online platform or speak with the support team. The Quercetin Dihydrate under the TriStains brand guarantees the availability of quality flavonoids to scientists and professionals, as well as to research centers. Quercetin Dihydrate (CAS: 6151-25-3) may also have a different price based on the quantity and the sourcing. The revised pricing information is available online and customers are able to compare competitive prices and a high level of adherence to quality standards to guarantee quality laboratory results.

About Brand

TriStains provides a marketplace for histology and biological stains, which is comprehensive enough to encompass the peculiar requirements of laboratories specializing in Histology, Cytology, Microbiology, and Hematology. With a reputation for exceeding quality expectations, TriStains performance is outstanding which allows for resolution of cell and tissue components fundamental to life sciences to be clearly visualized. Each product under TriStains series is validated for accuracy, reliability and consistency. TriStains, which manufactures and markets stains and indicators in various packing, offers laboratories turn key solutions for all their staining and indicator needs, improving accuracy in every experiment.

Additional information

Brand	Tristains
Size	100g, 10g, 25g, 50g, 5g
CAS No	6151-25-3

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TECHNICAL INFORMATION

Alternate Names	2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one dihydrate, 3,3,4,5,7-Pentahydroxyflavone dihydrate
Application	Quercetin Dihydrate is a natural flavonoid antiproliferative kinase inhibitor
CAS Number	6151-25-3
Molecular Weight	338.27
Molecular Formula	C15H10O7 · 2H2O
Supplemental Information	This is classified as a Dangerous Good for transport and may be subject to additional shipping charges

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Quercetin Dihydrate is the dihydrate preparation of Quercetin, a ubiquitous natural flavonoid with antiproliferative properties. Quercetin is described to inhibit PLA2 and PI 3-kinase (IC50 = 3.8 microM), blocking the ATP binding site of this kinase and interrupting the role of this enzyme in propagating cellular responses to growth factors. Quercetin is further described to inhibit nucleotide-dependent kinase enzymes through competition with ATP and GTP, demonstrating inhibition of pp60src phosphotransferase, tyrosine protein kinase, calcium- and phospholipid-dependent protein kinase, and cyclic GMP phosphodiesterases. Inhibition of PI 4-kinase (1-phosphatidylinositol 4-kinase) and PI-4-phosphate 5-kinase (1-phosphatidylinositol 4-phosphate 5-kinase) by Quercetin blocks the participation of these enzymes in signal transduction pathways and reduces cellular levels of the second messenger IP3 (inositol 1,4,5-trisphosphate), decreasing the release of intracellular Ca2+ stores. The antiproliferative and cytotoxic effects of Quercetin on cultured breast cancer cells are attributed to inhibition of PI 4-kinase and PI-4-phosphate 5-kinase, reduction of IP3 levels, and blockade of oncogenic growth signaling. Quercetin was shown to induce apoptosis in tumor cell lines at the G1 and S phases. Potential fatty acid synthase, PKC, and ATP5 (mitochondrial ATPase) inhibitor as well as an SIRT1 activator. SIRT1 deacetylates histones. Quercetin Dihydrate is an inhibitor of Pim-1 and an activator of GPR30.

TECHNICAL INFORMATION

Physical State	Solid
Solubility	Soluble in DMSO (68 mg/ml at 25° C), Acetic Acid (1 mg/ml), Aqueous Alkali (1 mg/ml), water (<1 at 25° C), and ethanol (21 mg/ml at 25° C).
Storage	Store at room temperature
Melting Point	310-315° C
Refractive Index	n20D 1.82 (Predicted)
IC50	Monoamine oxidase A: IC50 = 10 nM (bovine); CYP19: IC50 = 12 nM (human); Aldose Reductase: IC50 = 14.8 nM (human); Pim-1: IC50 = 43 nM (human); CYP1B1: IC50 = 77 nM (human)
Ki Data	D4DR: Ki= 7.8 nM (human); Enoyl-acyl-carrier protein reductase: Ki= 22 nM (plasmodium falciparum); CYP1B1: Ki= 23 nM (human); 5′-nucleotidase: Ki= 45.3 nM (rat); CYP1A1: Ki= 660 nM (human)

SAFETY INFORMATION

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

WGK Germany	3
RTECS	LK8950000
PubChem CID	5284452
Merck Index	14: 8034
MDL Number	MFCD00149487
EC Number	204-187-1
Beilstein Registry	317313
SMILES	C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O.O.O

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S10161

Quercetin dihydrate

CAS No

6151-25-3

Synonym(s)

2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one dihydrate, 3,3′,4′,5,7-Pentahydroxyflavone dihydrate

Molecular Formula:

C15H10O7 · 2H2O

Molecular Weight:

338.27

EC Number:

–

Colour Index Number:

PubChem CID:

5284452

MDL number:

Specification SDS Available pack size: 100g, 10g, 5g, 25g, 50g

Brand	Tristains
Size	100g, 10g, 25g, 50g, 5g
CAS No	6151-25-3

Alternate Names	2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one dihydrate, 3,3,4,5,7-Pentahydroxyflavone dihydrate
Application	Quercetin Dihydrate is a natural flavonoid antiproliferative kinase inhibitor
CAS Number	6151-25-3
Molecular Weight	338.27
Molecular Formula	C15H10O7 · 2H2O
Supplemental Information	This is classified as a Dangerous Good for transport and may be subject to additional shipping charges

Physical State	Solid
Solubility	Soluble in DMSO (68 mg/ml at 25° C), Acetic Acid (1 mg/ml), Aqueous Alkali (1 mg/ml), water (<1 at 25° C), and ethanol (21 mg/ml at 25° C).
Storage	Store at room temperature
Melting Point	310-315° C
Refractive Index	n20D 1.82 (Predicted)
IC50	Monoamine oxidase A: IC50 = 10 nM (bovine); CYP19: IC50 = 12 nM (human); Aldose Reductase: IC50 = 14.8 nM (human); Pim-1: IC50 = 43 nM (human); CYP1B1: IC50 = 77 nM (human)
Ki Data	D4DR: Ki= 7.8 nM (human); Enoyl-acyl-carrier protein reductase: Ki= 22 nM (plasmodium falciparum); CYP1B1: Ki= 23 nM (human); 5′-nucleotidase: Ki= 45.3 nM (rat); CYP1A1: Ki= 660 nM (human)

WGK Germany	3
RTECS	LK8950000
PubChem CID	5284452
Merck Index	14: 8034
MDL Number	MFCD00149487
EC Number	204-187-1
Beilstein Registry	317313
SMILES	C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O.O.O